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Pizza Mac and Cheese close-up with melted cheese and toppings.

Pizza Mac and Cheese: The Ultimate Comfort Food Recipe

Pizza Mac and Cheese combines creamy macaroni and cheese with the bold, zesty flavors of your favorite pizza toppings. It’s cheesy, hearty, and endlessly customizable—perfect for weeknights or casual gatherings.

  • Total Time: 45 minutes
  • Yield: 6 servings 1x

Ingredients

Scale
  • 1 pound elbow macaroni
  • 2 cups shredded mozzarella cheese
  • 1 cup shredded cheddar cheese
  • 2 cups pizza sauce
  • 1 cup cooked and crumbled Italian sausage (optional)
  • 1 cup sliced pepperoni
  • 1 bell pepper, diced
  • 1 small onion, diced
  • 1 teaspoon Italian seasoning
  • 1/2 teaspoon garlic powder
  • Salt and pepper to taste
  • 1/2 cup breadcrumbs (optional for topping)
  • 2 tablespoons butter
  • 2 tablespoons all-purpose flour
  • 1 cup milk or heavy cream

Instructions

  1. Preheat your oven to 350°F (175°C), if baking.
  2. Cook the macaroni in salted water until al dente. Drain and set aside.
  3. In a saucepan, melt butter over medium heat. Whisk in flour to make a roux and cook for 1 minute.
  4. Slowly whisk in milk, stirring until the sauce thickens.
  5. Reduce heat to low and add mozzarella and cheddar cheese. Stir until melted and smooth. Season with Italian seasoning, garlic powder, salt, and pepper.
  6. In a large bowl, mix the pasta, cheese sauce, and pizza sauce.
  7. Fold in sausage, pepperoni, bell pepper, and onion.
  8. Transfer to a greased baking dish, top with breadcrumbs and extra cheese, and bake for 25-30 minutes until bubbly and golden (optional).
  9. Let cool slightly before serving. Enjoy!

Notes

You can use gluten-free pasta or vegan cheese to meet dietary needs. Add veggies like mushrooms or spinach, or switch the sauce for Alfredo or pesto for a creative twist. Excellent for meal prep and repurposing as fritters or stuffed peppers.

  • Author: Fati
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Main Course
  • Method: Baking
  • Cuisine: American
  • Diet: Vegetarian

Nutrition

  • Serving Size: 1 cup
  • Calories: 450
  • Sugar: 6g
  • Sodium: 780mg
  • Fat: 24g
  • Saturated Fat: 11g
  • Unsaturated Fat: 10g
  • Trans Fat: 0g
  • Carbohydrates: 38g
  • Fiber: 3g
  • Protein: 20g
  • Cholesterol: 50mg

Keywords: Pizza Mac and Cheese, baked mac and cheese, pepperoni pasta, casserole, cheesy pasta bake